Clinical Research Registries
Join our research registries to contribute to medical knowledge and help advance treatments for various health conditions.
European Alpha-1 Research Collaboration (EARCO)
Who is this for?
Those with severe AATD, defined by an AAT serum level < 11 μM (50 mg/dl) and/or a proteinase inhibitor; genotype ZZ, SZ, and compound heterozygotes or homozygotes of other rare deficient variants (non-M)
Study:
EARCO collects prospective, non-interventional, multi-centre, standardized, longitudinal data on an international level necessary to evaluate the natural history of the disease; the influence of risk factors; other genetic determinants and the role of augmentation therapy in the prognosis of the disease elements
International Severe Asthma Registry (ISAR)
Who is this for?
Those with the following asthma symptoms: poor symptom control (ACQ >1.5, ACT < 20); serious and severe exacerbations; airflow limitation (post-bronchodilator FEV1 <80%)
Study:
ISAR is a global registry that collects anonymized, longitudinal, high-quality patient-level data via a standardized core set of variables. It provides the statistical power and opportunity to better understand severe asthma epidemiology across countries and regions and answer important research questions.